화학공학소재연구정보센터
학회 한국재료학회
학술대회 2009년 가을 (11/05 ~ 11/06, 포항공과대학교)
권호 15권 2호
발표분야 D. Health and Biological Materials(생체 및 의용재료)
제목 Electrospinning and mechanical characterization of hyaluronic acid nanofibers
초록 Electrospinning of a natural biopolymer, hyaluronic acid (HA), and the mass concentration-mechanical property relationship of the resulting nanofiber membranes have been investigated. It has been recognized that although HA can be easily dissolved in water the HA/water solution was unable to electrospin into ultra fine fibers. A different organic solvent, trifluoroacetic acid (TFA), is proven suitable for HA, and the resulting solution with a mass concentration in between 0.5 and 1.5% can be successfully electrospun into nanofibers of a diameter in a range from 200 to 600 nm. The decrease in surface tension could promote fiber formation. Thus, an introduction of TFA that could decrease the surface tension distinctively, without significant change or increase in viscosity of the solution, could bypass the use of blowing-assisted electrospinning. The physical properties of HA nano mat were characterized by SEM, X-ray diffraction (XRD), differential scanning calorimetry (DSC) and tensile strength.
저자 Yun Jin Soung1, Nguyen Thuy Ba Linh2, Hun Mo Yang3, Young Ki Min1, Byong-Taek Lee2
소속 1Department of Biomedical Engineering and Materials, 2School of Medicine, 3Soonchunhyang Univ.
키워드 Hyaluronic acid; Electrospinning; nanofiber; natural polymer
E-Mail