| 초록 |
Hydrogels have been widely used in biomedical areas, such as tissue engineering and drug delivery, due to their biocompatibility, flexibility, and wettability. In this study, the acrylic acid-based hydrogel was used for the formation of cell-including polymer matrices. The polymeric hydrogel matrices were prepared by swelling the hydrogel in water or DPBS (Dulbecco’s phosphate buffered saline). The cells were injected into the hydrogel matrices, and the viability of cells included inside the hydrogel matrices was analyzed. For the analysis of cell viability, the kidney epithelial 293 cells, transfected with GFP (green fluorescent protein)-expressing construct, were used. The persistent expression of GFP was observed, confirming the cell viability inside the hydrogel matrices. The formation of hydrogel matrices, adequate for the cell proliferation, could be used for the development of advanced wound-healing patches. |
