| 학회 |
한국고분자학회 |
| 학술대회 |
2018년 봄 (04/04 ~ 04/06, 대전컨벤션센터) |
| 권호 |
43권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
3D scaffolds based on FGNs beneficial to myogenesis |
| 초록 |
Over the last decade, there have been tremendous efforts to develop tissue engineering scaffolds for promoting cellular behaviors, including adhesion, proliferation and differentiation. Among them, particular attention has been paid to 3D scaffolds because cellular behaviors are directly dependent on the dimensional features of scaffolds. On the other hand, functional graphene nanomaterials (FGNs) have recently emerged as potential candidates due to their good biocompatibility and outstanding bioactivity. Herein, we prepared two types of FGN-functionalized 3D scaffolds [FGN-PU foams (GO-PFs) and FGN-gelatin hydrogels (GO-GHs)] and explored their potentials for myogenic differentiation thru cultivating skeletal myoblasts within both scaffolds. Our results showed that GO-PFs and GO-GHs have suitable 3D structures and could enhance myoblast growth and differentiation. Therefore, it is suggested that both FGN-based scaffolds can be effectively employed for myogenesis. |
| 저자 |
한동욱1, 신용철1, 송수진1, 강문성1, 홍석원1, 박기동2
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| 소속 |
1부산대, 2아주대 |
| 키워드 |
3D scaffolds; functional graphene nanomaterials; myogenesis
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| E-Mail |
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