초록 |
Surface plasmons at metal/dielectric interface resonate with the incident light generating the evanescent field at the interface, which is highly sensitive to the change in refractive index of the medium. Surface plasmon resonance (SPR)-based sensors with Kretschmann configuration provide label-free and real-time monitoring of binding interaction between probe and target moieties. However, it requires comparatively large size or high concentration of targets to make detectable change. In this regard, graphene was incorporated on top of Au film in order to increase the refractive index sensitivity. Graphene deposition on top of Au film led to the decrease of work function of the composite film, resulting in the increased surface dipole. Best RI sensitivity was obtained from the two layers of graphene by CVD which were turbostratically stacked to each other. Bio-affinity sensing performance was also evaluated using biotinylated bovine serum albumin and Streptavidin. |