화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터)
권호 38권 2호
발표분야 의료용 고분자 부문위원회
제목 Catechol-functionalized Ti-Adhesive Polymer Nanoparticles for Surface Drug-releasing Systems
초록 Titanium (Ti) has been widely used as a key material for orthopedic and dental implants due to its biocompatibility, resistance to corrosion, and excellent mechanical properties. To date, diverse surface treatment methods have been used to provide Ti implants with enhanced biocompatibility and bioactivity. Recently, surface treatments have focused on surface coatings that can induce controlled release of bioactive agents. However, most approaches are based on the solvent coating method, which has several drawbacks including irregular thickness and low interfacial adhesion between the coating and the implant surface. Herein, we suggest a catechol-functionalized adhesive nanoparticle as a surface coating system that may express enhanced adhesion to Ti surfaces and release osteogenic bioactive agents. Preparation of adhesive polymer nanoparticle was confirmed by dynamic light scattering and TEM. XPS and Fe-SEM verified successful immobilization of the nanoparticles onto Ti surfaces.
저자 제갈준호, 최기현, 이상천
소속 경희대
키워드 catechol; polymer; nanoparticle; drug; release
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