| 초록 |
Anti-oxidant materials such as polyphenols have received attention in many areas. However, their physicochemical properties have seldom been controlled for a specific target application. In this study, polymer-directed crystallization of catechin was performed by using a cooling crystallization. A mixed solution of catechin and polymer was cooled until catechin crystals appeared. When polyethylenimine (PEI), hydroxypropyl methylcellulose (HPMC) and polyvinyl alcohol (PVA) were used, the habits of catechin crystals were changed. In SEM results, the case of PEI, HPMC and PVA showed reduced crystals size compared to recrystallized catechin crystals. In the release tests, catechin with PVA and HPMC showed 50% lower initial release patterns and with PEI 90% sustained release pattern compared to recrystallized catechin. These results promised that the polymer-directed crystallization method could be effective for controlling the propertis of polyphenols with a limited amount of polymers. |
