| 학회 |
한국재료학회 |
| 학술대회 |
2014년 가을 (11/27 ~ 11/28, 대전컨벤션센터) |
| 권호 |
20권 2호 |
| 발표분야 |
D. 바이오 재료(Biomaterials) |
| 제목 |
Fabrication and evaluation of starch/PVA hydrogel for Tissue engineering application |
| 초록 |
Starch and polyvinyl alcohol has been widely used in packaging material and drug delivery due to its biodegradability low cost and renewability. In this study, different starch/pva hydrogel blends were fabricated using lyophilization with citric acid as cross-linker for tissue engineering application. Morphology of hydrogel was evaluated using SEM, and characterized using FTIR, contact angle measurement, swelling, degradation measurement and pore size distribution analysis. In-vitro study such as MTT assay and fluorescent staining using different cell lines (L929 cells, MC3T3-E1 pre-osteoblast cells and BMSC) were carried out to evaluate cytotoxicity adhesion, proliferation and in-vitro performance. Results of the study showed interconnected porosity, good swelling rate, slow degradation rate and no cytotoxic effect in-vitro, which make starch/PVA hydrogel suitable scaffold for different tissue engineering application. |
| 저자 |
Reiza D. Ventura1, Young Ki Min2, Byong-Taek Lee3
|
| 소속 |
1Department of Regenerative Medicine, 2College of Medicine, 3Soonchunhyang Univ. |
| 키워드 |
hydrogel; starch/PVA; characterization.
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| E-Mail |
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