| 초록 |
Malodor in wounds is mainly associated with exudating chronic wounds such as pressure ulcer, diabetic foot ulcer, fungating and malignant wounds. It is caused by the presence of anaerobic and aerobic bacteria. Metronidazole (MD) can control this malodor, but its oral use may cause adverse reactions. Therefore, MD hydrogel patches were prepared by using gamma irradiation. Measurement of swelling behavior of the MD hydrogel was performed in aqueous fluids such as water, simulated body fluid and horse serum. The developed odor-absorbing MD hydrogels will improve the quality of life for patients with malodorous ulcerated wounds and facilitate intensive treatment of the underlying disease. |
