| 학회 |
한국화학공학회 |
| 학술대회 |
2016년 봄 (04/27 ~ 04/29, 부산 BEXCO) |
| 권호 |
22권 1호, p.499 |
| 발표분야 |
생물화공 |
| 제목 |
Development of the Cadmium(Ⅱ) binding DNA Aptamer and the Affinity Test |
| 초록 |
Cadmium has no useful function in the higher organisms and high toxicity for the human body. Thus inappropriate level of cadmium exposure may cause renal dysfunction and can effect in the skeletal system. Recently, it has been released by many industrial waste, so it’s necessary to develop novel cadmium recovery material. Aptamer is small nucleic acid or peptide molecules that combine with specific target molecule. It has advantages of high selectivity and stability, low cost, easy modification. In the present study, we developed DNA aptamers that specifically combine with Cadmium by SELEX process. The affinity between target and aptamer was finally measured using SPR. This work was carried out with the support of “Cooperative Research Program for Agriculture Science & Technology Development(Project title: Development of Monitoring and Diagnostic method for Environment Animal Disease, Project No.: PJ010530)” Rural Development Administration, Republic of Korea. |
| 저자 |
윤수영1, 차지만1, 이상희1, Simranjeet Singh Sekhon1, 안지영1, 민지호2, 김양훈1
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| 소속 |
1충북대, 2전북대 |
| 키워드 |
바이오칩/나노바이오공학 |
| E-Mail |
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| 원문파일 |
초록 보기 |
