| 초록 |
Hydrogels have high water content, porous structure, relatively soft physical properties and characteristics similar to biological tissues. Therefore, hydrogels have been widely studied and applied in biomaterials for cell culture, drug delivery, biosensors, and tissue engineering. Specifically, photo-responsive hydrogels have advantages that we can tune the mechanical properties of hydrogels in real time with minimal invasion by external stimulations. Here, we made photo-reversible hydrogels using pdDronpa, a photo-reversible green protein, and 8-Armed PEG-maleimide. It showed reversible swelling-shrinking by cyan and violet light, respectively. This hydrogel could be applied to light-controllable drug delivery system. |
