| 초록 |
The catechol functional group of dopamine (3,4-dihydroxy phenethylamine) has characteristics of strong coordination with inorganic and organic materials in aqueous system. And, one of the most common approach to provide nonfouling surfaces is through the immobilization of poly(ethylene glycol), so called PEGylation. In this work, the adhesive polyaspartamides containing catechol and methoxy PEG pendants were synthesized from polysuccinimide through a serious of aminolysis reactions. The adhesion & crosslinking of dopamine-PEG-modified polyaspartamide in pH controlled aqueous media (pH 8.5) was successfully utilized to modify inorganic glass and organic poly(ethylene terephthalate) thin film using a simple immersion process. The coated substrates were analyzed by contact angle measurement, SEM & EDS, XPS, AFM analysis. In addition the cell-viability test was performed to prove non-cytotoxic character of the modified surfaces. |
