| 학회 |
한국화학공학회 |
| 학술대회 |
2008년 봄 (04/23 ~ 04/25, 제주ICC) |
| 권호 |
14권 1호, p.334 |
| 발표분야 |
분리기술 |
| 제목 |
The Study of the Retention Models for the Separation of ortho-xylene and para-xylene in Reverse-Phase Chromatography Using Solvent-Gradient Operation |
| 초록 |
The solvent-gradient operations in a batch chromatography give significant improvements in term of the enrichment of products, the separation time and the solvent consumption as compared with the isocratic operations. A different mobile phase composition leads to a different retention behavior of solutes owing to different interactions between solute and stationary phase. This work studied about solvent-gradient operation of the reversed-phase chromatography for the separation of ortho-xylene and para-xylene. To estimate a correlation of isothermal adsorption equilibrium with varying solvent composition for ortho-xylene and para-xylene, multi-step frontal analysis experiments were carried out at five different mobile phase compositions, such as 45%, 50%, 60%, 75% and 90% of acetonitrile. And, it was confirmed that the correlations in a retention model for the solvent-gradient operation in the reversed-phase chromatography agree well with the experimental results by performing a simulation. |
| 저자 |
롱벤덱, 레타이황, 김진일, 이주원, 김정근, 구윤모
|
| 소속 |
인하대 |
| 키워드 |
Solvent-gradient; o-xylene; p-xylene; Reversed-phase liquid chromatography
|
| E-Mail |
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| 원문파일 |
초록 보기 |
