| 학회 |
한국고분자학회 |
| 학술대회 |
2008년 봄 (04/10 ~ 04/11, 컨벤션 뷰로(대전)) |
| 권호 |
33권 1호 |
| 발표분야 |
의료용 고분자 |
| 제목 |
Preparation and Characterization of Cisplatin-Loaded Carboxymethyl Chitosan Nanoparticles |
| 초록 |
Carboxymethyl chitosan(CMCh) was prepared by chemical reaction with mono-chloroacetic acid and glyoxylic acid to low molecular weight water soluble chitosan(LMWSC) of C6-OH (O-Carboxymethyl chitosan) and C2-NH2 (N-Carboxymethylc chitosan) group to apply asgene and drug carrier. Cisplatin (cis-dichlorodiammineplatinum(II): CDDP) is one of the most widely used antitumor drugs in the treatment of a variety of solid tumors. CDDP loaded CMCh nanoparticles were prepared by ion-complex and investigated by 1H-NMR,FT-IR (Fourier transform infrared), SEM (scanning electron microscopy), DLS (dynamic light scattering) measurement. |
| 저자 |
남정표, 김동곤, 정영일, 김명렬, 장미경, 나재운
|
| 소속 |
순천대 |
| 키워드 |
carboxymethyl chitosan; Water-soluble chitosan; cisplatin
|
| E-Mail |
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