| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 봄 (04/11 ~ 04/12, 대전컨벤션센터) |
| 권호 |
38권 1호 |
| 발표분야 |
대학원생 구두발표(발표10분) |
| 제목 |
Multi-functional poly(ethylene glycol) hydrogel microparticle containing nanofiber microarchitectures |
| 초록 |
A simple method to generate well-defined microscopic architectures composed of electrospun nanofibers is reported and their potential applications to biomedical fields were studied. The photopatterning of polyethylene glycol (PEG) hydrogel on electrospun polycarprolactone (PCL) nanofibers leads to the formation of two different microdomains in nanofibrous mats: a bare nanofiber region and a hydrogel-entrapped nanofiber region. The selective dissolution of bare nanofibers with an organic solvent enables the localization of PCL nanofibers within the hydrogel microstructures. Microparticles are ultimately obtained, the size and shape of which can be easily controlled with proper photomask designs. We also expect that the PEG hydrogel can also provide a protective environment for the nanofibers by preventing the non-specific adsorption of various molecules onto the nanofibers and improving the biocompatibility of microarchitectured nanofibers. |
| 저자 |
이현종, 한상원, 고원건
|
| 소속 |
연세대 |
| 키워드 |
Electrospinning; PEG hydrogel microaprticle; Nanofibrous microarchitecture
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| E-Mail |
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