학회 | 한국공업화학회 |
학술대회 | 2013년 봄 (05/01 ~ 05/03, ICC JEJU) |
권호 | 17권 1호 |
발표분야 | 포스터-정밀화학 |
제목 | Synthesis of Pyridazine Derivatives for Diels-Alder reactions |
초록 | The hetero Diels-Alder reaction is one of the most important methods for the synthesis of heterocycles. A plethora of different acyclic and cyclic diaza dienes has been employed, and pyridazine derivatives have received significant attention as electron-deficient dienes in an inverse-demand Diels-Alder reactions. Herein, we will report synthesis of various pyridazine derivatives. The malonyl, nitromethyl, and nitrile groups were introduced to prepare the strongly electron-deficient diens. Successful functionalization of them into several synthetic building blocks was also achieved. |
저자 | 강은실, 홍연우, 강재식, 김영규 |
소속 | 서울대 |
키워드 | Pyridazine; inverse-demand Diels-Alder reaction |