화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2002년 가을 (10/24 ~ 10/26, 서울대학교)
권호 8권 2호, p.2869
발표분야 공정시스템
제목 DNA 마이크로어레이를 이용한 암 관련 유전자 탐색
초록 Upcoming the era of postgenomic, various important data are produced from biological and medical experiments such as DNA microarray, 2D-PAGE, blotting and so on. Although these data includes many significant biological meaning and concepts, it is hard to find out useful and significant knowledge from multidimensional raw data because these data contain noises and faults from the non-automatic experiment and the change of various experiment conditions. Then, bioinformatics (especially data analysis) is spotlighted in all area of biology because data analysis technique can give statistical and biological annotation with more systematical approach. For the gene expression data, the following systematical data analysis steps are needed. 1)Collection of DNA chip data 2)Check of statistical significance of differential gene expression 3)Normalization of DNA microarrays 4)Selection of the significant genes 5)Elucidation of biological phenomena from the gene expression patterns
저자 박진현, 이동권, 최상욱, 조지훈, 김명수, 김덕희, 이인범
소속 (주)피앤아이컨설팅
키워드 Cancer; Biplot; clustering; Microarray; monitoring
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