| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Preparation and Release Properties of Allopurinol Imprinted MEL_MBS Nonoparticles |
| 초록 |
This study focuses on the prepared of allopurinol (ALP) imprinted MEL_MBS nanoparticles (MEL_SNPs) using mungbean starch (MBS), melanin (MEL) as a photothermal agent, and crosslinking agents (trisodium trimetaphosphate (STMP) and sodium tripolyphosphate (STPP)). The SNPs were prepared using water/oil emulsion method. The prepared SNPs were characterized by FT-IR, FE-SEM, TEM, DLS analysis. Photothermal effects of MEL_SNPs were evaluated with NIR laser irradiation. Results of DLS anlaysis, particle size distributions were confirmed that MEL_SNPs formed nanoparicles with mean diameter 186.03nm. The results of NIR laser irradiated at SNPs with/without the addition of MEL, the temperature increase of MEL_SNPs were higher than SNPs. This results indicate that MEL_SNPs has photothermal effect due to the addition of MEL as a photothermal agent. The results of ALP release properties of MEL_SNPs with NIR laser irradiation indicated that ALP release rate of MEL_SNPs were faster than SNPs. |
| 저자 |
김한성, 김경중, 이시연, 조은비, 황민진, 김은식, 윤순도
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| 소속 |
전남대 |
| 키워드 |
MEL_MBS nanoparticles; Melanin; Allopurinol; Release properties; particle size distribution; Photothermal effect
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| E-Mail |
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