| 초록 |
The adhesive hydrogel is extensively used as a biomaterial for diverse medical applications due to its excellent biocompatibility. In this work, bio-inspired adhesive IPN hydrogels were prepared by the L-3,4-dihydroxyphenylalanine derivatives and Polyacrylamide(PAAm) that can be efficiently and rapidly activated with an initiator and a cross-linker without the external stimuli. We fabricated a tough hydrogel with high strain sensitive features and strong adhesive for different kinds of substrate. Additionally, to induce the formation of catechol-metal coordination interactions, metal cations(Ca2+, Fe3+, V5+) were added to the network hydrogel of PAAm/DOPA derivative copolymers, and their mechanical properties were evaluated and characterized. This study provides a stretchable and adhesive hydrogel based on a mussel-inspired copolymer for their potential applications in the biomaterials field even wet condition. |
