| 학회 |
한국공업화학회 |
| 학술대회 |
2015년 봄 (04/29 ~ 05/01, BEXCO (부산)) |
| 권호 |
19권 1호 |
| 발표분야 |
(정밀화학) 기능성 소재를 활용한 조직 공학 응용 |
| 제목 |
Oxygen releasing 3D scaffolds for prolonged cell survival under hypoxic environment |
| 초록 |
The survival of cells in the 3D scaffold until the ingrowth of blood vessels is one of the most important challenges in tissue engineering for producing a clinically relevant volume of tissue. In this study, oxygen carrier-loaded 3D matrices were prepared as a scaffolding system which can allow release of oxygen to cells adhered on the matrices to prevent cell necrosis in a hypoxic environment (inherently created in tissue engineered 3D constructs) until new blood vessels are formed in the 3D cell construct, and thus may produce appropriate tissues/organs with a clinically relevant volume. Based on the in vitro and in vivo findings, the oxygen carrier-loaded 3D matrices can be a promising system to produce a clinically applicable large tissue mass. |
| 저자 |
이해영1, 김해원1, 이진호2, 오세행1
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| 소속 |
1단국대, 2한남대 |
| 키워드 |
Tissue engineering; Oxygen delivery; Scaffold
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| E-Mail |
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