| 초록 |
In this study, surface response methodology was used to optimize the medium composition for the production of astaxanthin by Paracoccus sp.. A screening test was first conducted on 5 medium components using a Plackett-Burman design, from which MgSO4 and yeast extract were identified as the significant factors affecting astaxanthin production. These significant factors were optimized by central composite design of experiments and response surface methodology. With the optimized medium compositions, the experimentally obtained concentration of astaxantin was 1.021 mg/L, where it had been 0.4 mg/L before optimization. |
