| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
38권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Hydrogel-Incorporated Nanofiber Scaffolds for Biomedical Applications |
| 초록 |
In this presentation, a simple method to generate well-defined microscopic architectures composed of electrospun nanofibers and their potential application to biomedical fields are described. The photopatterning of polyethylene glycol (PEG) hydrogel on electrospun polymeric nanofibers led to the formation of two different microdomains in nanofibrous mats: a bare nanofiber region and a hydrogel-entrapped nanofiber region. If microwell-shaped hydrogel micropatterns were fabricated, resultant micropatterned nanofiber matrices was capable of generating cell and protein micropatterns due to the different interactions that cells and proteins have with PEG hydrogels and nanofibers. We demonstrated that resultant hydrogel-incorporated nanofiber scaffolds could be utilized for studying cell-cell interaction and controlling stem cell fate. |
| 저자 |
고원건1, 이현종2, 이혜원2, 박상필2, 정의석2
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| 소속 |
1연세대, 2연세대 화공생명공학과 |
| 키워드 |
hydrogel patterns; nanofibers; cell and protein micropatterns; stem cells
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| E-Mail |
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