| 학회 |
한국고분자학회 |
| 학술대회 |
2022년 봄 (04/06 ~ 04/08, 대전컨벤션센터) |
| 권호 |
47권 1호 |
| 발표분야 |
콜로이드 및 분자조립 부문위원회 |
| 제목 |
Hierarchical Fiber Structures of Amyloid Fibrils through Evaporation-Induced Self-Assembly |
| 초록 |
Amyloid fibrils are protein-based anisotropic colloids that are formed by the self-assembly of β-sheet aggregates. The helical ribbons have recently been highlighted as building blocks due to unique molecular functionality. But, to the best of our knowledge, there is little consideration about a combination between the molecular characteristics and structural properties. We try to integrate the liquid crystal (LC) properties of amyloid fibrils with evaporation-induced self-assembly. Aqueous amyloid solutions are sequentially dried under the restricted geometry and examined the highly ordered and aligned LC textures through a polarized optical microscope. The self-assembly mechanisms are rationalized from demonstrating the stick-and-slip action of amyloid fibrils in real-time. The morphology can be tuned by varying the width of the topographic templates and the resultant aggregates are used as templates for forming arrayed gold nanoparticles that show excellent conductivity. |
| 저자 |
박순모, 윤동기
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| 소속 |
한국과학기술원 |
| 키워드 |
Amyloid fibrils; Evaporation-induced self-assembly; Stick-and-slip motion; Hierarchical structure; Topographic substrate
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| E-Mail |
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