| 초록 |
The monomer sequence of peptide-mimic polymer may determine the structure and function of chain, as the sequence of amino acids in a natural protein would. Understanding polymerization kinetics would be helpful in bringing the monomer sequence of synthetic polymer up to the protein’s level. A class of synthetic helical polymers, “polyisocyanates”, which consist of rigid nylon-1 backbone and N-substituted side chains, have a potential merit of artificial models to mimic the peptide dynamics. The concept of chain polymerization of isocyanates was first reported by Victor E. Shashoua in 1969, and the technologies for living anionic polymerization of isocyanates were developed by Jae-Suk Lee from 1999. This presentation shares my study to define the kinetic principles of living anionic polymerization of isocyanates. This work purposed to develop a new synthetic technology that can greatly expand the limit of monomer sequences attainable in polyisocyanates as peptide-mimic polymers. |
