| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO)) |
| 권호 |
25권 2호 |
| 발표분야 |
학생우수논문발표(석사과정) |
| 제목 |
Functional Niacinamide imprinted starch based biomaterials for treatment of hyperpigmentation |
| 초록 |
The aims of this study were to prepared functional biomaterials for application to the treatment of hyperpigmentation using niacinamide (NA), mungbean starch (MS), polyvinyl alcohol (PVA), and plasticizers (glycerol (GL) and citric acid (CA)). The functional biomaterials were characterized and evaluated for FE-SEM and FT-IR, and physical properties. The NA release properties indicated that NA was released rapidly until the initial 10 min and that NA release in low pH was slightly faster than in high pH. The result of NA release using artificial skin confirmed that 100% of NA was released for 3 h. To verify the functionality of the prepared biomaterials, tyrosinase inhibitory and DPPH assay were further performed. These results indicated that NA imprinted biomaterials with the addition of CA exhibited 52% of tyrosinase inhibition and 73% of free radical scavenging activity rate. Additionally, the inhibition of melanin synthesis in B16F10 cells was evaluated. |
| 저자 |
이시연1, 김경중1, 조은비1, 이창문1, 심왕근2, 윤순도1
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| 소속 |
1전남대, 2순천대 |
| 키워드 |
Niacinamide; hyperpigmentation; Tyrosinase inhibitory; DPPH assay; Melanin synthesis
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| E-Mail |
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