화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2009년 봄 (04/09 ~ 04/10, 대전컨벤션센터)
권호 34권 1호
발표분야 기능성 고분자
제목 The preparation of a PVP-micropatterned surface by an ion irradiation for the manipulation of cellular behavior
초록 In this study, thin poly(vinyl pyrrolidone) (PVP) films prepared by a spin-coating on polymer dishes were irradiated through a pattern mask with 200 keV proton at fluences between 1 x 1014 and 1 x 1016 ions/cm2. Afterwards, the irradiated samples were developed to generate the PVP patterns. The ion beam irradiation effect on the PVP patterns was investigated by using FT-IR spectroscopy and water contact angle measurement. Cell culturing on the PVP patterns revealed that the cells were preferentially adhered and proliferated on the PVP patterns, thereby generating well-defined 100 μm cell patterns.
저자 안미영1, 황인태2, 정찬희3, 노영창1, 최재학4, 허강무1
소속 1Advanced Radiation Technology Institute, 2Korea Atomic Energy Research Institute / Department of Polymer Science and Engineering, 3Chungnam National Univ., 4Korea Atomic Energy Research Institute
키워드 PVP; cell pattern; ion-beam
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