| 초록 |
Single DNA strands recognize their complements and precisely pair with one another. Explicit selectivity of both strands makes DNA a promising nano-building block for the achievement of novel polymeric architectures. One example of DNA blocks is a Holliday junction, which possesses a tripodal spot formed by a simple combination of three different oligonucleotides During the self-assembly of different numbers of oligonucleotides comprising junctional DNA nanostructures, a change in environmental variables has a substantial influence on the final products. Here, we present an evaluation of the annealing characteristics of oligonucleotides for the formation of a simple junctional DNA nanostructure using an annealing curve analysis. This method may be useful for analyzing the formation of complex junctional DNA nanostructures. |
