화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center))
권호 24권 1호
발표분야 포스터-생체재료
제목 Immunogenic cell death-inducible nanobubbles for cancer immunotherapy
초록 Recently, immunogenic cell death has emerged as an alternative method for utilizing dying cancer cells to elicit an antitumor immune response through conventional anticancer therapy. However, proteolysis and oxidation of alarmins during the apoptotic process occur irreversible loss of immunogenicity. Here, we report nanobubble-induced immunogenic cell death that can induce the release of intact damage-associated molecular patterns and tumor-associated antigens through physical disruption of the cellular membrane.
저자 엄우람, 고혜원, 박재형
소속 성균관대
키워드 Reactive oxygen species; nanobubble; cancer therapy
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