| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 |
| 제목 |
Characteristics of retinal pigment epithelial cells cultured on SIS sheets |
| 초록 |
Transplantation of RPE is a promising treatment modality to repair retinal damage in age-related macular degeneration. For this purpose, it is necessary to establish cell culture techniques that allow acquisition of proper functional and morphological characteristics by the cells to be transplanted. The transplantation of pigment epithelial cells as a therapeutic modality for retinal degeneration requires that the transplanted cells form a monolayer in the subretinal space that will establish communication with photoreceptors. To establish cell monolayers, retinal pigment epithelial cells were cultured on SIS sheets. Cells were examined for morphology, for characteristics of differentiation and viability. These studies have shown that RPE cells adhere, proliferate, form monolayers, and acquire differentiated properties on SIS sheets. Therefore, The SIS sheet could act as a potential scaffold to enhance the RPEs proliferation. This research was supported by WCU(R31-20029). |
| 저자 |
김수진, 조은혜, 정수미, 김은영, 이은용, 이동원, 강길선
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| 소속 |
전북대 |
| 키워드 |
Retinal pigment epithelial cell; SIS sheet; Proliferation; phenotype maintenance; scaffold
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| E-Mail |
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