초록 |
The rapid and differential detection of Gram-negative infections would greatly reduce the overuse of antibiotics, and minimize the spread of antibiotic resistance. However, conventional diagnostics relies on microbial culture which is time-consuming, while molecular methods involve complex processing procedures. Herein, we studied the use of antibiotics as a targeting ligand for ubiquitous detection of Gram-negative bacteria. We chose colistin as the targeting ligand, which includes cationic residues (L- |