| 학회 |
한국공업화학회 |
| 학술대회 |
2007년 가을 (11/02 ~ 11/03, 한경대학교) |
| 권호 |
11권 2호 |
| 발표분야 |
우수논문(구두) |
| 제목 |
Development of low molecular weight water soluble chitosan gene carrier fractioned according to molecular weight |
| 초록 |
To obtain low molecular weight water soluble chitosan(LMWSC) with various molecular weights, the crude chitosan oligosaccharides(COS) was separated according to its molecular weight by using ultrafiltration technique. LMWSC with a free amine group was prepared by the novel salts-removal method. The characterization of fractioned LMWSC and degree of deacetylation were identified by GPC, FT-IR and 1H-NMR spectra. To identify potential as a gene carriers, Successfully fractioned COS and salt-removed LMWSC confirmed transfection efficiency using 293T cell. |
| 저자 |
장민자, 허선행, 김동곤, 이종완, 조안나, 오인환, 박영훈, 장미경, 나재운
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| 소속 |
순천대 |
| 키워드 |
LMWSC; COS; Gene carriers; Transfection efficiency
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| E-Mail |
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