| 학회 |
한국재료학회 |
| 학술대회 |
2018년 가을 (11/07 ~ 11/09, 여수 디오션리조트) |
| 권호 |
24권 2호 |
| 발표분야 |
B. 나노화학/바이오 재료 분과 |
| 제목 |
A strategy for senstive detection of microRNA |
| 초록 |
Rapid develpment of nanotechnology provides significant improvement in vitro diagnostics(IVD) systems. Among the nanomaterials, gold have received considerable research interest due to its virtues, including unique enhanced electromagnetic field, ease of synthesis and functionalization, and excellent biocompatibility and stability. The unique physicochemical properties of gold nanomaterials provide various specific signal transducers like LSPR and SERS and amplification strategies like electrochemical signal and fluorescence enhanecement, both of which can be harnessed to created IVD assays with appropriate clinical featurs. Here, we presented a simple and reliable method to detection microRNAs, which is controlled diverse gene expression, using gold nanoparticles and molecular beacons. These systems would be contributed our fundamental understanding for disease research and treatment. |
| 저자 |
기지선1, 이효영2, 한승민2, 장은지2, 허용민2, 함승주2
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| 소속 |
1연세대하교 화공생명공학과, 2연세대 |
| 키워드 |
<P>microRNA; Molecular beacons; gold nanoparticles</P>
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| E-Mail |
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