| 초록 |
Poly(ethylene glycol) diacrylate (PEGDA) is one of photopolymerize-able scaffold compound by acrylate crosslinking. PEGDA is tunable and high mechanical strength material. Graphene oxide (GO) can assist to PEGDA's cell adhesion property by plate function of cells. In this paper, we suggest acrylate-catechol surface primer for connecting PEGDA with GO without reaction to preserve PEGDA's mechanical strength and hold the site of GO. We treated surface primer to GO and confirmed the properties by zeta potential, solubility test and XRD. Also we observed SEM and EDS to investigate each GO size and distribution of carbon and oxide groups. After Photopolymerization of PEGDA with primed GO, we first proceed the compression test and confirmed the increase of mechanical strength compared to PEGDA without treating GO. Second, we cultured MG63 cells into PEGDA with GO gels and proceed the ELISA to analyze the increase of TGF beta-1 release. |
