| 학회 |
한국공업화학회 |
| 학술대회 |
2020년 가을 (10/28 ~ 10/30, 광주 김대중컨벤션센터(Kimdaejung Convention Center)) |
| 권호 |
24권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Functional Nanoparticles for Engineering and Tracking of Immune Cell Therapeutics |
| 초록 |
Recently, natural killer (NK)-based immunotherapy has attracted attention as a next-generation cell-based cancer treatment strategy due to its mild side effects and excellent therapeutic efficacy. However, the attempts of the molecular engineering of NK cells have been challenged by the low efficiency of gene delivery into this cell type. In vivo monitoring of NK cell trafficking is also crucial in studying NK cell behavior under physiological conditions and evaluating the efficiency of adoptive transfer. we described functional nanoparticles capable of genetically engineering NK cells, as well as in vivo MR and fluorescence optical imaging. |
| 저자 |
김광수1, 한준혁2, 한동근1, 박우람3, 박경순1
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| 소속 |
1차의과학대, 2고려대, 3가톨릭대 |
| 키워드 |
Nanoparticles; Immunotherapy; NK cells; Cancer; Bioimaging
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| E-Mail |
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