화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2006년 봄 (04/20 ~ 04/21, 대구 인터불고 호텔)
권호 12권 1호, p.300
발표분야 분리기술
제목 Separation of L-Phenylalanine from a Ternary Amino Acid Mixture Using Two-Zone SMB/Chromatography Hybrid System
초록 For a center-cut separation, which is separation of only the middle (intermediate retained) component from a ternary mixture, current technology requires either adjustment of adsorbent properties to make it the least or most retained component or use of a cascade with multiple simulated moving bed (SMB) systems. Unfortunately, adjustment of the adsorbent may not be possible, and a cascade with two four-zone SMBs requires at least eight columns and is complex and expensive.

In this study, we have designed a semicontinuous, center-cut, two-zone SMB/chromatography system to separate L-Phenylalanine, which is the middle compoenent, from a mixture of Glycine, L-Phenylalanine, and L-Tryptophane. Experiments were conducted at low concentrations so that the isotherms are linear, and a Genetic Algorithm was used to determine operating conditions. Experimental results show that the two-zone hybrid system can be used for center-cut separation from ternary mixture with reasonable purity and Dtotal/F.
저자 허진석1, 김진일2, 김정근2, Phillip C. Wankat1, 구윤모2
소속 1Purdue Univ., 2인하대
키워드 SMB; Chromatography; Ternary Separation; Center-Cut Separtion
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