초록 |
Wound healing is the one of the major issues in the health care field. Especially, skin damage is the common injury because skin plays a role as a physiological barrier between organs and external environment. In this regards, accelerating skin regeneration is important to prevent chronic wound that results in the infection problems by pathogens. Herein, we report multifunctional biocompatible hydrogel for effective wound healing process, which retains moisture environment around wound and deliver drug by porous structure for promoting tissue proliferation. Janus interface structure is attributed to not only protect vulnerable damaged tissue from external fouling and invasion of pathogens also fix hydrogel on skin stably under movement without tape. Furthermore, self healing property enables to recover the defects of hydrogel, caused by mechanical stress, and prevent the generation of debris from damaged hydrogel. These factors attribute to enhance skin regeneration. |