화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2021년 봄 (04/07 ~ 04/09, 대전컨벤션센터)
권호 46권 1호
발표분야 기능성 고분자
제목 Multi-functional porous polysaccharide based coating for intravascular catheters
초록 Intravascular catheters are commonly used medical devices for patients in order to hemodynamic monitoring, medication administration, etc. Intravascular catheterization have several critical issues such as damage of blood vessel due to high friction, blood stream infection, blood coagulation. Herein, we attempted to functionalized the surface of catheter using O-carboxymethyl chitosan (CMC) which is a polysaccharide possessing lubricity, antimicrobial and anticoagulant activity. The hydrophobic catheter surface was modified with acrylic acid by electron beam induced grafting, leading to strong interfacial adhesion between grafted polyacrylic acid and CMC. The CMC coating layer was fabricated as a porous structure using Poly ethylene glycol. As a result, the coated surface exhibited superhydrophilicity under specific fabrication conditions. Furthermore, the effects of various pore system on the performance of functional coated catheter surface were discussed.
저자 박세계1, 신재학2, 정재희2, 이동윤3, 최동윤1, 유승화4
소속 1한국생산기술(연), 2세종대, 3경북대, 4전북대
키워드 Multi-functional coating; Intravascular catheters; Superhydrophilicity; Antimicrobial activity; Anticoagulant activity
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