| 학회 | 한국공업화학회 |
| 학술대회 | 2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU)) |
| 권호 | 26권 1호 |
| 발표분야 | 포스터-생체재료 |
| 제목 | Inflammation control in human gingival fibroblast cells by cold atmospheric plasma for application in periodontal disease |
| 초록 | The aim of this study is to study the anti-inflammatory effects of cold-atmospheric plasma (CAP) against human gingival fibroblast-1 (HGF-1) cells. CAP apparatus was designed to study in periodontal disease in vitro. HGF-1 cells were treated with lipopolysaccharide (LPS) and inflammatory response was evaluated. The CAP treatment was not significantly affected to the viability of HGF-1 cells. When LPS was treated to HGF-1cells, secretion of inflammatory cytokines such as IL-6, IL-8 and TNF-α was increased compared to the control group. Cell viability was also decreased by treatment of inflammatory cytokines. However, the secretion of inflammatory cytokines from LPS-treated HGF-1 cells was significantly decreased when CAP was treated to cells. Furthermore, cell viability was also increased compared to LPS-treated cells. Acknowledgement: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. 2020R1A2C2008540). |
| 저자 | 정영일1, 국민석2, 김병훈1 |
| 소속 | 1조선대, 2전남대 |
| 키워드 | Cold atmospheric plasma; reactive oxygen species; inflammation; Human gingival fibroblast |
