| 초록 |
For effective application and further utilization of DNA hydrogels, highly effective methods of nano- and micro-scale DNA hydrogel fabrication are needed. In this respect, the fundamental advantages of a core-shell structure can provide a simple remedy. An isolated reaction chamber and massive production platform can be provided by a core-shell structure, and lipids are one of the best shell precursor candidates due to their intrinsic biocompatibility and potential for easy modification. Here, we demonstrate a novel core-shell nanostructure made of gene-knitted X-shaped DNA origami-networked gel core-supported lipid strata. It was simply organized by crosslinking DNAs via T4 enzymatic ligation and enclosing them in lipid strata. As a condensed core structure, DNA gel shows Brownian behavior in confined area. |
