화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터)
권호 15권 1호
발표분야 정밀화학
제목 Synthesisof carboxymethyl chitosan(CH6-OH position)-g- Poly(Ethylene imine) for DNA delivery system
초록 For successful gene therapy is safe and effective gene delivery system development is needed. Chitosan to form complexes with DNA degradation by DNase, these complexes has been reported that there is an effect. They have a high positive charge that the PEI with the DNA complex formation is easy. With the application of these characteristics, we have prepared carboxymethyl chitosan((CH6-OH), OCMch) and Poly(ethylene imine) PEI. OCMch-PEI was prepared by chemical reaction with OCMCh and PEI for DNA delivery system.
저자 김영민, 이경재, 남정표, 박준규, 김원석, 최창용, 나재운, 장미경
소속 순천대
키워드 O-carboxymethyl chitosan; Poly(ethylene imine); DNA
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