화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU))
권호 26권 1호
발표분야 포스터-생물공학
제목 High-throughput analysis of genetic variation utilizing high resolution microchip-based CE-SSCP
초록 Capillary electrophoresis on microchip-based genetic analysis systems are very usefulbecause of rapid analysis, tiny sample/reagent consumption, and portability. Among the many other electrophoretic techniques, capillary electrophoresis-single strand conformation polymorphism (CE-SSCP) analysis is one of promising genotyping method due to its simplicity and versatility. In this study, a high-resolutionmicrochip CE-SSCP system was demonstrated by using an optimum condition (300μmchannel width with PEO-PPO-PEO triblock copolymer). This analysis system was successfully applied to the various genetic analyses including food-bornepathogen detection and single nucleotide polymorphism marker detection.​
저자 문조현, 신기영, 정규열
소속 포항공과대
키워드 Genetic analysis system; synthetic biology; high-resolution microchip
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