초록 |
Capillary electrophoresis on microchip-based genetic analysis systems are very usefulbecause of rapid analysis, tiny sample/reagent consumption, and portability. Among the many other electrophoretic techniques, capillary electrophoresis-single strand conformation polymorphism (CE-SSCP) analysis is one of promising genotyping method due to its simplicity and versatility. In this study, a high-resolutionmicrochip CE-SSCP system was demonstrated by using an optimum condition (300μmchannel width with PEO-PPO-PEO triblock copolymer). This analysis system was successfully applied to the various genetic analyses including food-bornepathogen detection and single nucleotide polymorphism marker detection. |