화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2005년 가을 (10/21 ~ 10/22, 인하대학교)
권호 11권 2호, p.1686
발표분야 고분자
제목 pH and temperature sensitive hydrogels of poly(ethylenglycol) and poly(aminoester)
초록 pH and temperature sensitive hydrogels were synthesized from Polyethylene glycol – poly D, L. Lactide - ε-caprolactone (PCLA-PEG-PCLA); or Polyethylene glycol – poly ε-caprolactone (PCL-PEG-PCL), N. N’ trimethylenedipiperidine, piperazine, and butanediol diacrylate, hexandiol diacrylate to make pentablock β.aminoester-PCLA-PEG-PCLA - β.aminoester or β.aminoester-PCL-PEG-PCL - β.aminoester. The sol-gel transition properties of these block copolymers are influenced by the hydrophobic/hydrophilic balance of the copolymer, block length, hydrophobicity, stereo-regularity of the hydrophobic of the block copolymer1, and the ionization of the pH function groups in the copolymer depended on the changing of environmental pH.
The result of the investigation can be used for drug and protein delivery field.
저자 현다이푸, 이두성
소속 성균관대
키워드 pH and temperature sensitive; hydrogel; aminoester
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