| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Hyperbranched Poly(glycidol) / Poly(ethylene oxide) Hydrogel Microporous Scaffold for Skin Tissue Engineering |
| 초록 |
A microporous hydrogel scaffold was developed from Hyperbranched Polyglycidol (HPG) and Poly(ethylene oxide) (PEO) using an electron beam induced crosslinking for skin tissue engineering applications. It was found that the pore size of hydrogel scaffold increased by increasing the HPG content as well as elongation at break, which are the most useful properties of a scaffold in tissue engineering. Meanwhile the tensile strength of all compositions of the HPG/PEO hydrogel scaffold is strong enough for tissue engineering eventhough the cross-linking density decreases slightly by increasing HPG content in the hydrogel. The degree of the degradation of crosslinked hydrogel films increased by increasing the HPG content. Finally, the cytocompatibility of hydrogels was evaluated by in vitro culture of fibroblast cells. The results proved that cell viability and proliferation of 20% HPG/PEO hydrogel scaffold accelerate cell infiltration and proliferation most effectively. |
| 저자 |
김성철 |
| 소속 |
영남대 |
| 키워드 |
Hyperbranced polyglycidol; microporous scaffold; elongation at break; crosslinking; electron beam; skin tissue engineering
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| E-Mail |
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