| 학회 |
한국고분자학회 |
| 학술대회 |
2022년 봄 (04/06 ~ 04/08, 대전컨벤션센터) |
| 권호 |
47권 1호 |
| 발표분야 |
대학원생 구두발표(발표15분) |
| 제목 |
Bioprinting cell-laden tissue constructs using visible light crosslinkable bioinks |
| 초록 |
Bioprinting is a rapidly developing technique to fabricate functional tissues and organs. Among many bioprinting techniques, photocrosslinking based bioprinting allows to prepare 3D complex hydrogels with tissue-specific properties. However, poor biocompatibility and low photoreactivity of existing bioinks limit their use in the fabrication of cell-laden 3D tissue constructs. Here, we report a fast-curable low-energy bioprinting system using a photosensitive hyaluronic acid (HA) and water-soluble photoinitiator (PI) for visible light-induced 3D bioprinting. After examining the water solubility, molar extinction coefficients, photocrosslinking efficiency and biocompatibility of the PIs, corneal structure was fabricated and the cell viability in the 3D-printed constructs were evaluated. Overall, the HA-based bioinks exhibited superior properties to function as a fast-curing visible light-induced 3D printing material suitable for cell-laden tissue constructs for tissue engineering. |
| 저자 |
이경원1, Ajeesh Chandrasekharan2, 김소담3, 성금용4, 양승윤1
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| 소속 |
1Department of Biomaterials Science (BK21 Four Program), 2Pusan National Univ., 3Miryang 50463, 4Republic of Korea |
| 키워드 |
tissue engineering; 3D bioprinting; hyaluronic acid; bioink
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| E-Mail |
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