화학공학소재연구정보센터
학회 한국화학공학회
학술대회 2022년 봄 (04/20 ~ 04/23, 제주국제컨벤션센터)
권호 28권 1호, p.964
발표분야 [주제 12] 화학공학일반(부문위원회 발표)
제목 Process Systems Engineering in Biopharmaceuticals: Modeling Study of Freeze-Drying
초록 Rapid mass production and transportation of biopharmaceuticals are highly recommended, especially in response to the pandemic situation these days. Freeze-drying enables effective storage and transport that prevents heat-sensitive products from getting damaged. However, a lengthy drying time is a bottleneck of the freeze-drying process that microwave application for biopharmaceuticals has been experimentally tried to overcome its limitation. In this study, an early model of microwave applied freeze-drying is developed where no simple mechanistic model existed before. As a result, the drying time is reduced by over 70% in the model, displaying reasonable temperature and drying time predictions.



This work was supported by the “Program of Fostering Innovative Global Leaders” of the Korea Institute for Advancement of Technology (KIAT) with financial support by the Ministry of Trade, Industry & Energy (MOTIE), Republic of Korea (P0008747).
저자 박진우1, 조재현2, Richard D. Braatz3
소속 1공주대, 2연세대, 3MIT
키워드 공정시스템(Process Systems Engineering)
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