| 학회 |
한국공업화학회 |
| 학술대회 |
2008년 가을 (11/12 ~ 11/14, ICC 제주) |
| 권호 |
12권 2호 |
| 발표분야 |
콜로이드계면화학 심포지엄 |
| 제목 |
Ultrasound Imaging of Antibody-labeled Microbubbles |
| 초록 |
We report the preparation of micro/nano bubbles with an antibody (anti-CD147) for ultrasound contrast agents and the ultrasound imaging for the bubbles.Newly synthesized cycloamylose-modified surfactant and polymerizable cationic gemini surfactant were used to prepare “nanobubbles”. Then an antibody (anti-CD147) which selectively adsorbs on tumor cells due to antigen-antibody reaction was labeled to microbubbles.Ultrasound imaging for the microbubbles labeled with anti-CD147 was tried using a Radial Flow Bioreactor (RFB). The anti-CD147-labeled microbubbles were accumulated on the liver tumors, and clearly imaged by ultrasound for 10 min after injection to the RFB. |
| 저자 |
Masahiko Abe |
| 소속 |
Faculty of Science and Technology |
| 키워드 |
micro/nano bubble; surfactant; ultrasound; antibody; tumor cell
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| E-Mail |
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