| 초록 |
DNA block copolymers are hybrid polymers that contain both DNA and synthetic polymer linked into a blocky chain structure. They represent a special class of charged-neutral block copolymers that can potentially interact with cationic molecules to form polyelectrolyte complexes. Here, we prepare DNA-poly(ethylene glycol) (DNA-PEG) block copolymer and investigate its complexation with ionic liquid (IL). Thermal annealing is employed to induce complex micelle formation, and the micelle morphology is investigated by varying DNA hybridization state, IL type, and charge ratio. The hybridization state of the DNA is found to play a critical role in determining the complex formation. While ssDNA-PEG does not interact effectively with IL, dsDNA-PEG complexes well with IL to form stable micelles over a large range of charge ratios. Additionally, the anion type of the IL also affects the morphology and stability of the complexes which may be attributed to the differences in anion hydrophilicity. |
