| 초록 |
Continuous intraocular pressure monitoring has been extensively investigated as a new paradigm in the management of patients with glaucoma. Despite these efforts, the sensitivity and stability of strain sensors operated by wireless power and communication systems in smart contact lenses have limited the practical applications for IOP monitoring. Here, we have developed a smart contact lens integrated with a transparent AgNW IOP sensor and wireless circuits for continuous, non-invasive IOP monitoring. After confirming the robust stability of the IOP sensor in the smart contact lens in the presence of tears and repeated eyelid blink model cycles, we were able to monitor IOP changes on PDMS model eyes in vitro. In vivo tests demonstrated that our fully integrated, wireless smart contact lens could successfully monitor the change of IOP in living rabbit eyes. Taken together, we could confirm the feasibility of our smart contact lens as a non-invasive platform for monitoring changes in IOP. |
