| 학회 |
한국고분자학회 |
| 학술대회 |
2017년 봄 (04/05 ~ 04/07, 대전컨벤션센터) |
| 권호 |
42권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Biodegradable Nanofiber by Solution Blow Spinning for Hepatic Trauma use of Surgicla Sealant in Vivo |
| 초록 |
Solution blow spinning is a technique for depositing polymer fibers with promising potential use as a surgical sealant. For surgical sealant feasibility testing in a mouse model study was then used to demonstrate some of the possible surgical applications including use as a surgical hemostatic, a surgical sealant, and for tissue reconstruction. The fabricated of a functionalized nanofiber was demonstrated as a surgical sealant by solution blow spinning, and the characteristics of adapt to various surface substrate using commercial airbrush. Solution and deposition conditions of biodegradable polymer nanofibers were optimized and mechanical properties confirmed by dynamic mechanical analysis. Nanofibers degradation degree was monitored of morphology and molecular weight by different conditions in vitro. Biocompatibility of nanofibers onto cell lines was indicated in vitro and blood interaction was evaluated with FE-SEM(Field-emission Scanning Electron Microscopy). |
| 저자 |
홍상은, 윤국로
|
| 소속 |
한남대 |
| 키워드 |
Biodegradable polymer; Nanofiber; Solution Blow Spinning; Surgical sealant; Hepatic Trauma
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| E-Mail |
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