화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO))
권호 21권 2호
발표분야 우수논문(구두)_박사과정
제목 Biodegradable Polymeric Nanofiber Containing Hemostatic agent as Surgical Sealant and Anti-adhesive for Liver Trauma
초록 Biocompatible nanofiber and scaffolds have been widely researched for biomedical applications. Fabricated of a biodegradable nanofiber was demonstrated as a surgical sealant and anti-adhesive by solution blow spinning. Solution blow spinning is a technique for depositing polymer fibers with promising potential use as a surgical sealant. Characterization of adapt to various surface substrate using commercial airbrush. Solution and deposition conditions of biodegradable polymer nanofibers were optimized and mechanical properties confirmed by dynamic mechanical analysis. Nanofibers degradation degree was monitored of morphology and molecular weight by various conditions in vitro. MTT cell viability assay of human coronary atrial endothelial cells (HCAEC) were performed. Biodegradable nanofiber of animal study demonstrated that the wide potential of this technique across numerous surgical applications, including its use as a surgical sealant, hemostatic, and support for tissue repair.
저자 홍상은, 윤국로
소속 한남대
키워드 biodegradable nanofiber; solution blow spinning; surgical sealant
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