| 초록 |
Among various wearable devices, a contact lens is especially noticeable for healthcare applications because it can be used as an efficient interface between a human body and the electronic device. Here, we developed a smart contact lens for theranosis of diabetic retinopathy as a model for wirelessly powered healthcare systems. The smart contact lens is composed of four miniaturized components: a real-time electrochemical biosensor, a self-regulated pulsatile drug delivery system, a wireless power transfer system by resonant inductive coupling, and a complementary metal–oxide-semiconductor integrated circuit based microcontroller chip. Connected with a wireless communication electronic device, tear glucose level could be measured as a non-invasive alternative to the conventional blood glucose tests. Furthermore, we successfully demonstrated the controlled pulsatile drug delivery from gold coated reservoirs integrated within remotely powered lens for ocular theranostic applications. |
